專任教授(生物醫學組)-中央大學生命科學系資訊網

• 現  職：

1. 國立中央大學 生命科學系 副教授 (2024~present)

• 學  歷：

1. 美國紐約大學  生物學/發育遺傳學 博士 (2004~2011)
2. 美國紐約大學  生物學/發育遺傳學 碩士 (2002~2004)
3. 國立中興大學  分生所/分子生物 碩士 (1995~1998)
4. 國立彰化師範大學  生物系 學士 (1991~1995)

• 經  歷：

1. 國立中央大學 生命科學系 副教授 (2024~present)
   
2. 國立中央大學 助理教授 (2016~2024)
3. 美國紐約大學生物學 博士後研究員 (2011~)
4. 長庚醫學院醫技系 研究助理 (2000~2002)

• 授  課

1. 功能性基因體學
2. 普通生物學
3. 生物技術
4. 專題研究:基礎果蠅遺傳學與胚胎發育
   

期   刊

1. Liang CH, Nien CY, Chen YL, Hsu KW.   "The prevalence and associated factors of proximal contact loss between implant restoration and adjacent tooth after function: A retrospective study."  Clin Implant Dent Relat Res.   2020 May 17. doi: 10.1111/cid.12918. Online ahead of print. PMID: 32419242

2. Lin HD, Wang FZ, Lee CY, Nien CY, Tseng YK, Yao CL, Chen SC.  "4-Aminobiphenyl inhibits the DNA homologous recombination repair in human liver cells: The role of miR-630 in downregulating RAD18 and MCM8"  Toxicology. 2020 May 17;440:152441. doi: 10.1016/j.tox.2020.152441. Online ahead of print. PMID: 32433928
   
3. (*Co-first author) Sun Y*, Nien C*, Chen K, Liu H, Johnston J, Koenecke N, Zeitlinger J, & Rushlow C, (2015) Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation. Genome Res. 25(11):1703-14. IF: 11.351
4. Foo S, Sun Y, Lim B, Ziukaite R, O'Brien K, Nien C, Kirov N, Shvartsman SY, & Rushlow C (2014) Zelda potentiates morphogen activity by increasing chromatin accessibility. Curr Biol. 16:24(12):1241-6. IF: 9.916
5. Fu S, Nien C, Liang H, & Rushlow C (2014) Co-activation of microRNAs by Zelda is essential for early Drosophila development. Dev. 141(10):2108-18. IF: 6.2
6. Hong X, Doddapaneni H, Comeron JM, Rodesch M, Halvensleben H, Nien C, Bolei F, Metpally R, Richmond TA, Albert TJ, & Manak JR (2012) Microarray-based capture of novel expressed cell type-specific transcripts (CoNECT) to annotate tissue specific transcript isoforms in D. melanogaster.  G3. 2:873-882. IF: 2.511
7. (*Co-first authored) Nien C*, Liang H*, Liu H, Butcher S, Sun Y, Fu S, Gocha T, Kirov N, Manak JR, & Rushlow C (2011) Temporal coordination of gene networks by Zelda in the early Drosophila embryo. PloS Genet. 7(10): e1002339. IF: 8.167
8. (*Co-first authored) Liang H*, Nien, C.*, Liu H, Metzstein M, Kirov N, & Rushlow C (2008) The zinc-finger protein Zelda is a key activator of early zygotic genome in Drosophila. Nature. 456(7220): 400-3. IF: 42.351
9. Yen H, Nien C, Majima H, Lee C, Chen S, & Wei J (2002) Increase of lipid peroxidation by cisplatin in WI38 cells but not in SV40-transformed WI38 cells. J Biochem Mol Toxicol. 17(1): 39-46. IF: 1.596
10. Yen H, Cheng H, Hsu Y, Ho H, Nien C, & Lee Y (2001) Effects of age and health status on levels of urinary 15-F2t-isoprostane. J Biomed Lab Sci. 13(1): 24-28.

• 2009 ~ 2010
  Dean’s Dissertation Award, Graduate School of Science, New York University
• 2009
  Annual Drosophila research conference Poster Award, The Genetics Society of America.
• 2009
  Charlotte Pann Research Award, New York University
• 2004 ~ 2011
  MacCracken Fellowship, New York University
  

• 碩士班學生：范毓婷、黃乙統、張鈺、吳芳瑜、張騰元