Full-time Professors (Biomedicine)-Department of Life Sciences, NCU

1. Position: Associate Professor
2. Education:
1. Ph.D., Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 2001-2008
2. M.S., Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 1999-2001
3. B.S., Department of Life Science, College of Science, National Cheng Kung University, Tainan, Taiwan, 1994-1999/01
3. Professional Experience:
   1. Associate Professor, National Central University (2023-present)
      
   2. Assistant Professor, National Central University (2018-2023)
      
   3. 2011/01-2018/07 Postdoctoral fellow (National Institute of Environmental Health Sciences, National Health Research Institutes)
   4. 2008/08-2010/12  Postdoctoral fellow (Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University)
   5. 2001/09-2008/06 Teaching assistant of immunology experiment course
   6. 1999/09-2001/01 Teaching assistant of microbiology experiment course
4. Contact:886-3-422-7151 ext 65075
5. FAX:(03) 422-8482
6. E-mail:yhluo@cc.ncu.edu.tw

Scientific Journal reports

1. Wang CW, Lin P, Chen YC, Luo YH, Wu CD, Li CC, Lin CH R. (2025) Long-term air pollution exposure and mortality outcomes in colorectal cancer patients: Evidence from a multicenter longitudinal study. Cancer Epidemiology, 99:102948. (IF=2.3; SCI, R/C=172/421, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH).

2. Cheng HJ#, Hsu WL#, Lin P, Chen YC, Lin TH, Fang SS, Tsai MH, Lin YJ, Wang SP, Chen H, Jan MS, Luo YH* (# equal contribution) (2024) Involvement of autophagy and gut dysbiosis in ambient particulate matter-induced colonic inflammation. Ecotoxicology and Environmental Safety, 286:117171 (IF=6.1; SCI, R/C=7/106, TOXICOLOGY). (* Correspondence)

3. Wu PY, Hasanah U, Yang SH, Chen SY, Luo YH, Chen CC, Chen SC. (2024) Enhancing cisplatin efficacy in hepatocellular carcinoma with selenocystine: The suppression of DNA repair and inhibition of proliferation in hepatoma cells. Chemico-Biological Interactions, 405:111291 (IF=5.4; SCI, R/C=57/353, PHARMACOLOGY & PHARMACY).

4. Arrokhman S, Luo YH, Lin P * (2023) Additive cardiotoxicity of a bisphenol mixture in zebrafish embryos: The involvement of calcium channel and pump. Ecotoxicology and Environmental Safety, 263:115225 (IF=6.1; SCI, R/C=7/106, TOXICOLOGY)

5. HsuWL, Wang CM, Yao CL, Chen SC, Nien CY, Sun YH, Tseng TY, Luo YH* (2022) Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through P62-Keap-1-Nrf2 axis, Cell Death & Disease, 13(12):1060 (IF=9.6; SCI, R/C=37/204, CELL BIOLOGY)

6. Wahyuni EA, Yii CY, Liang HL, Luo YH, Yang SH, Wu PY, Hsu WL, Nien CY*, Chen SC* (2022). Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells, Chemico-Biological Interactions, 365:110046 (IF=5.4; SCI, R/C=57/353, PHARMACOLOGY & PHARMACY)

7. Jhong JH, Tsai WH, Yang LC, Chou CH, Lee TY, Yeh YT, Huang CH and Luo YH* (2022). Heat-killed Lacticaseibacillus paracasei GMNL-653 exerts antiosteoporotic effects by restoring the gut microbiota dysbiosis in ovariectomized mice, Frontiers in Nutrition, 9:804210 (IF=5.1; SCI, R/C=24/112, NUTRITION & DIETETICS)

8. Lee CW, Hsu LF, Wu I.L, Wang YL, Chen WC, Liu YJ, Yang LT, Tan CL, Luo YH, Wang CC, Chiu HW, Yang TCK, Lin YY, Chang HA, Chiang YC, Chen CH, Lee MH, Peng KT, Huang CCY * (2022) Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice. Journal of Hazardous Materials, 430: 128431. (IF=11.3; SCI, R/C=24/374, ENVIRONMENTAL SCIENCES)

9. Nguyen MHT, Luo YH, Li AL, Tsai JC, Wu KL, Chung PJ, Ma N *(2021). miRNA as a modulator of immunotherapy and immune response in melanoma. Biomolecules, 11(11):1648. (IF=4.8; SCI, R/C=125/320, BIOCHEMISTRY & MOLECULAR BIOLOGY)

10. Gudivada VN, Huang CJ, Luo YH, and Dong GC * (2021) A cyclic BMP-2 peptide upregulates bmp-2 protein-induced cell signaling in myogenic cells. Polymers (Basel), 13(15): 2549. (IF=4.9; SCI, R/C=19/94, POLYMER SCIENCE)

11. Lin HD, Yao CL, Ou WJ, Luo YH, Chen SC* (2020). 4-Aminobiphenyl suppresses homologous recombination repair by a reactive oxygen species-dependent p53/miR-513a-5p/p53 loop. Toxicology, 444, 152580. (IF=4.6; SCI, R/C=10/106, TOXICOLOGY)

12. Luo YH*, Cheng HJ, Tsai FY, Tsou TC, Lin SY, Lin P.* (2020). Primary amine modified gold nanodots regulate macrophage function and antioxidant response: potential therapeutics targeting of Nrf2. International Journal of Nanomedicine, 15, 8411-8426. (IF=6.5; SCI, R/C=53/353, PHARMACOLOGY&PHARMACY). (* Correspondence)

13. Luo YH, Kuo YC, Tsai MH, Ho CC, Tsai HT, Hsu CY, Chen YC, Lin P*. (2017) Interleukin-24 as a target cytokine of environmental aryl hydrocarbon receptor agonist exposure in the lung. Toxicology and applied pharmacology. 324:1-11 (IF=3.4; R/C=20/106, TOXICOLOGY)

14. Ho CC, Lee HL, Chen CY, Luo YH, Tsai MH, Tsai HT, Lin P*. (2017) Involvement of the cytokine-IDO1-AhR loop in zinc oxide nanoparticle-induced acute pulmonary inflammation. Nanotoxicology. 11(3):360-370 (IF=3.4; R/C=58/106, TOXICOLOGY)

15. Ho CC, Luo YH, Chuang TH, Lin P*. (2016) Quantum dots induced interferon beta expression via TRIF-dependent signaling pathways by promoting endocytosis of TLR4. Toxicology. 344-346:61-70 (IF=4.6; SCI, R/C=10/106, TOXICOLOGY)

16. Luo YH, Wu ZW, Tsai HT, Lin SY, Lin P*. (2015) Endotoxin nanovesicles: hydrophilic gold nanodots control supramolecular lipopolysaccharide assembly for modulating immunological responses. Nano letters. 15(10):6446-6453 (IF=9.1; R/C=28/241, CHEMISTRY, MULTIDISCIPLINARY)

17. Luo YH, Chang LW, and Lin P*. (2015) Metal-based nanoparticles and the immune system: activation, inflammation and potential applications. BioMed Research International. 143720. (IF=2.3; R/C=93/177, BIOTECHNOLOGY & APPLIED MICROBIOLOGY)

18. Cheng HJ, Luo YH, Lei HY, Lin CF, Wang ST, Chen KJ, Hung NT, Liu CC, Liu HS, Yeh TM, Lin YS*. (2015) Correlation between serum levels of anti-endothelial cell autoantigen and anti-dengue virus nonstructural protein 1. American Journal of Tropical Medicine and Hygiene. 92(5):989-95. (IF=1.6; R/C=11/28, TROPICAL MEDICINE)

19. Lu SL, Tsai CY, Luo YH, Kuo CF, Lin WC, Chang YT, Wu JJ, Chuang WJ, Liu CC, Chao L, Chao J, Lin YS*. (2013) Kallistatin modulates immune cells and confers anti-inflammatory response to protect mice from group a streptococcal infection. Antimicrobial Agents and Chemotherapy. 57(11):5366-5372. (IF=4.5; R/C=60/353, PHARMACOLOGY & PHARMACY)

20. Ho CC, Luo YH, Chuang TH, Yang CS, Ling YC, Lin P*. (2013) Quantum dots induced monocyte chemotactic protein-1 expression via MyD88-dependent Toll-like receptor signaling pathways in macrophages. Toxicology. 308:1-9. (IF=4.6; SCI, R/C=10/106, TOXICOLOGY)

21. Luo YH, Wu SB, Wei YH, Chen YC, Tsai MH, Yang CS, Lin P*. (2013) Cadmium-based quantum dot induced autophagy formation for cell survival via oxidative stress. Chemical Research in Toxicology. 26:662-673. (IF=3.8; R/C=34/106, TOXICOLOGY)

22. Li MH*, Luo YH*, Lin CF, Chang YT, Hong JS, Lin YS. (*equal contribution) (2011) Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses, and prevents group A streptococcal sepsis. Antimicrobial Agents and Chemotherapy. 55:967-973. (IF=4.5; R/C=60/353, PHARMACOLOGY & PHARMACY)

23. Luo YH, Chuang WJ, Wu JJ, Lin MT, Liu CC, Lin PY, Roan JN, Wong TW, Chen YL, Lin YS*. (2010) Molecular mimicry between streptococcal pyrogenic exotoxin B and endothelial cells. Laboratory Investigation. 90:1492-1506. (IF=4.2; R/C=27/195, MEDICINE, RESEARCH & EXPERIMENTAL)

24. Cheng HJ, Lei HY, Lin CF, Luo YH, Wan SW, Liu HS, Yeh TM, Lin YS*. (2009) Anti-dengue virus nonstructural protein 1 antibodies recognize protein disulfide isomerase on platelets and inhibit platelet aggregation. Molecular Immunology. 47:398-406. (IF=3.0; R/C=90/183, IMMUNOLOGY)

25. Cheng HJ, Lin CF, Lei HY, Liu HS, Yeh TM, Luo YH, Lin YS*. (2009) Proteomic analysis of endothelial cell autoantigens recognized by anti-dengue virus nonstructural protein 1 antibodies. Experimental Biology and Medicine. 234:63-73. (IF=2.7; R/C=107/195, MEDICINE, RESEARCH & EXPERIMENTAL)

26. Luo YH, Kuo CF, Huang KJ, Wu JJ, Lei HY, Lin MT, Chuang WJ, Liu CC, Lin CF, Lin YS*. (2007) Streptococcal pyrogenic exotoxin B antibodies in a mouse model of glomerulonephritis. Kidney International. 72:716-724. (IF=12.6; R/C=4/133, UROLOGY & NEPHROLOGY)

27. Kuo CF, Chen CC, Lin CF, Jan MS, Huang RY, Luo YH, Chuang WJ, Sheu CC, Lin YS*. (2007) Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines. Food and Chemical Toxicology. 45:278-285. (IF=3.5; R/C=47/181, FOOD SCIENCE & TECHNOLOGY)

28. Kuo CF, Chen CC, Luo YH, Huang RY, Chuang WJ, Sheu CC, Lin YS*. (2005) Cordyceps sinensis mycelium protects mice from group A streptococcal infection. Journal of Medical Microbiology. 54:795-802. (IF=2.0; R/C=123/163, MICROBIOLOGY)

29. Wang CH, Lin CY, Luo YH, Tsai PJ, Lin YS, Lin MT, Chuang WJ, Liu CC, Wu JJ*. (2005) Effects of oligopeptide permease in group A streptococcal infection. Infection and Immunity. 73:2881-2890. (IF=2.8; R/C=70/137, INFECTIOUS DISEASES)

30. Kuo CF, Luo YH, Lin HY, Huang KJ, Wu JJ, Lei HY, Lin MT, Chuang WJ, Liu CC, Jin YT, Lin YS*. (2004) Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection. Microbial Pathogenesis. 36:273-285. (IF=3.5; R/C=68/163，MICROBIOLOGY)